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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCCC2
All Species:
34.85
Human Site:
Y196
Identified Species:
63.89
UniProt:
Q9HCC0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC0
NP_071415.1
563
61333
Y196
D
H
F
G
R
T
F
Y
N
Q
A
I
M
S
S
Chimpanzee
Pan troglodytes
XP_517717
563
61220
Y196
D
H
F
G
R
T
F
Y
N
Q
A
I
M
S
S
Rhesus Macaque
Macaca mulatta
XP_001096794
563
61647
Y196
S
H
I
T
F
H
F
Y
N
L
V
I
M
E
S
Dog
Lupus familis
XP_535268
563
61534
Y196
D
H
F
G
R
I
F
Y
N
Q
A
I
M
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULD5
563
61361
Y196
D
H
F
G
R
I
F
Y
N
Q
A
I
M
S
S
Rat
Rattus norvegicus
Q5XIT9
563
61499
Y196
D
H
F
G
R
I
F
Y
N
Q
A
I
M
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091355
562
61332
Y195
D
H
F
G
R
I
F
Y
N
Q
A
R
M
S
S
Zebra Danio
Brachydanio rerio
NP_998092
566
61725
F199
D
H
F
G
R
I
F
F
N
Q
A
R
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9A7
578
62630
Y195
L
H
F
G
R
I
F
Y
N
Q
A
N
M
S
A
Honey Bee
Apis mellifera
XP_394033
559
61367
F191
M
H
F
G
R
T
F
F
N
Q
A
R
M
S
A
Nematode Worm
Caenorhab. elegans
P34385
608
66505
Y241
Q
H
F
G
R
I
F
Y
N
Q
A
T
M
S
S
Sea Urchin
Strong. purpuratus
XP_001201046
552
59601
F185
E
H
F
G
R
I
F
F
N
Q
A
T
M
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDD8
587
63994
Y214
E
N
F
G
R
V
F
Y
N
E
S
V
M
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93
87.9
N.A.
88.8
88.2
N.A.
N.A.
N.A.
81.5
81
N.A.
67.4
69
59.2
65.5
Protein Similarity:
100
99.1
95.3
93.7
N.A.
94.3
94.3
N.A.
N.A.
N.A.
90.4
89.2
N.A.
78.7
82.5
74.5
79.5
P-Site Identity:
100
100
46.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
86.6
73.3
N.A.
73.3
73.3
80
66.6
P-Site Similarity:
100
100
46.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
86.6
86.6
N.A.
80
86.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
58
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
73
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
85
0
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
93
0
8
0
100
24
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
93
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
62
0
0
0
0
0
47
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
100
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
85
0
0
0
0
0
% Q
% Arg:
0
0
0
0
93
0
0
0
0
0
0
24
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
8
0
0
93
77
% S
% Thr:
0
0
0
8
0
24
0
0
0
0
0
16
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _